|
| 產(chǎn)地 | 進(jìn)口、國(guó)產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號(hào) | CS11986 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| CAS編號(hào) | |
| 抗體名 | Anti-UBXD2 |
| 克隆性 | |
| 靶點(diǎn) | 詳見(jiàn)說(shuō)明書(shū) |
| 適應(yīng)物種 | 詳見(jiàn)說(shuō)明書(shū) |
| 形態(tài) | 詳見(jiàn)說(shuō)明書(shū) |
| 宿主 | 詳見(jiàn)說(shuō)明書(shū) |
| 亞型 | IgG |
| 標(biāo)識(shí)物 | 詳見(jiàn)說(shuō)明書(shū) |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human UBXD2 (201-300aa) |
全、新、優(yōu)、品、好四大特點(diǎn)：
UBX結(jié)構(gòu)域域蛋白D2抗體規(guī)格 全：公司提供上萬(wàn)種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過(guò)程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒(méi)有任何的后顧之憂。
UBX結(jié)構(gòu)域域蛋白D2抗體規(guī)格 英文名稱 Anti-UBXD2
中文名稱 UBX結(jié)構(gòu)域域蛋白D2抗體規(guī)格
別 名 Erasin; FLJ23318; KIAA0242; KIAA2042; UBX domain containing 1; UBX domain containing 2; UBX domain containing protein 2; UBXD 2; UBXDC 1; UBXDC1; UBXN4_HUMAN.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來(lái)源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep
產(chǎn)品類型 一抗
研究領(lǐng)域 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) Alzheimer's
蛋白分子量 predicted molecular weight: 57kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human UBXD2 (201-300aa)
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
UBX結(jié)構(gòu)域域蛋白D2抗體規(guī)格 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Erasin is an endoplasmic reticulum (ER) and nuclear envelope membrane protein. Expressed in a variety of tissues, such as brain, placenta, heart, liver, prostate, kidney, pancreas, lung and skeletal muscle, erasin contains one UBX domain and participates in the clearing of ERAD (endoplasmic reticulum-associated protein degradation) substrates. The UBX domain of erasin is responsible for mediating its direct interaction with VCP (valosin-containing protein), an AAA-ATPase molecular chaperone. In response to ER stress, erasin expression is induced. The knockdown of erasin expression leads to the inhibition of ERAD, suggesting an important function of erasin in the ERAD pathway. In addition, erasin may be involved in Alzheimer’s disease, as it is known to accumulate in neurofibrillary degenerating neurons in patients with Alzheimer’s disease.
Function : UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP) and promotes ER-associated protein degradation (ERAD). Immunohistochemical staining of brain tissue from patients with Alzheimer's disease and control subjects revealed that UBXD2 accumulates preferentially in neurons undergoing neurofibrillary degeneration in Alzheimer's disease.
Subunit : Directly interacts with VCP.
Subcellular Location : Endoplasmic reticulum membrane. Both the N- and the C-terminus face the cytosol; also found in the nucleus envelope contiguous to the ER.
Tissue Specificity : Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level).
Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity : Contains 1 UBX domain.
Database links : UniProtKB/Swiss-Prot: Q92575.2
實(shí)驗(yàn)流程：
正在熱銷的相關(guān)產(chǎn)品：
PAFR/PTAFR 血小板活化因子受體抗原Multi-class antibodies規(guī)格： 0.5mg
Anti-AT1R/AGTR1 緊張素Ⅱ-1型受體抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh phospho-APP/ABPP(Ser198) 磷酸化APP淀粉樣肽前體蛋白抗體 規(guī)格 0.1ml
Stat3 濃縮液 0.1ml 進(jìn)口分裝
UBE2D1 英文名稱： 泛素蛋白連接酶D1抗體 0.2ml
DENND1B 英文名稱： DENND1B蛋白抗體 0.2ml
Anti-AT1R/AGTR1 緊張素Ⅱ-1型受體抗體Multi-class antibodies規(guī)格： 0.2ml
OPG ELISA Kit 大鼠骨保護(hù)素Multi-class antibodies規(guī)格： 48T
Anti-Amph/FITC 熒光素標(biāo)記神經(jīng)元突觸前膜蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh FASTKD1 Fas活化激酶結(jié)構(gòu)域蛋白1抗體 規(guī)格 0.2ml
PF3(Mouse platelet factor 3) ELISA Kit 小鼠血小板因子3 96T
MAP4K1 英文名稱： 造血祖細(xì)胞激酶1抗體 0.1ml
AKAP2 英文名稱： 蛋白激酶A2抗體 0.2ml
Anti-Amph/FITC 熒光素標(biāo)記神經(jīng)元突觸前膜蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Anti-TRH/FITC 熒光素標(biāo)記促甲狀腺素釋放激素抗體IgGMulti-class antibodies規(guī)格： 0.2ml
CA15-3 peptide 癌相關(guān)抗原抗原Multi-class antibodies規(guī)格： 0.5mg
阻抑基因1抗體 Anti-TSLC1 0.2ml
STIP1 英文名稱： 應(yīng)激誘導(dǎo)磷蛋白1抗體 0.2ml
Endomucin 英文名稱： 內(nèi)皮粘蛋白EMCN抗體 0.2ml
Rhesus antibody Rh Phospho-IRAK1 (Thr387) 磷酸化白介素-1受體相關(guān)激酶1抗體 規(guī)格 0.1ml
CA15-3 peptide 癌相關(guān)抗原抗原Multi-class antibodies規(guī)格： 0.5mg
大鼠可溶性細(xì)胞間粘附分子1(sICAM-1)ELISA 試劑盒 96T/48T 試劑盒 組裝/原裝
人神經(jīng)激肽B(NKB)免疫試劑盒 Human Neurokinins B,NKB ELISA Kit
MousehepatitisBvirussurfaceaigen,HBsAgELISAKit小鼠表面抗原(HBsAg)ELISA試劑盒規(guī)格：96T/48T
CASPASE-10蛋白表達(dá)西方雜交分析試劑盒5次
Humanmethoexate,MTXELISA試劑盒人喋呤(MTX)ELISA試劑盒規(guī)格：96T/48T
Humanplateletfactor3，PF3ELISAKit人血小板因子3(PF-3)ELISA試劑盒規(guī)格：96T/48T
大鼠白細(xì)胞介素10(IL-10)ELISA試劑盒 ，英文名： IL-10 ELISA Kit
Mouse macrophage migration inhibitory factor (MIF) ELISA Kit 小鼠巨噬細(xì)胞移動(dòng)抑制因子(MIF)ELISA試劑盒
Mouseosteoclastdiffereiationfactor,ODFELISAKit 小鼠破骨細(xì)胞分化因子(ODF)ELISA試劑盒 96T/48T 進(jìn)口分裝
CLIAKitforHumanNephrinELISAKit人蛋白規(guī)格：48T/96T
銅藍(lán)蛋白活性比色法定量檢測(cè)試劑盒20次
ELISAKitB7-2/sCD86大鼠可溶性白細(xì)胞分化抗原86規(guī)格：48T/96T
UBX結(jié)構(gòu)域域蛋白D2抗體規(guī)格 大鼠催產(chǎn)素受體(OX)ELISA試劑盒 ，英文名： OX ELISA Kit
P cadherin / placeal cadherin (P-cad) ELISA Kit 人P鈣黏蛋白/胎盤(pán)鈣黏蛋白(P-cad)ELISA試劑盒
Ratbrainnaiureticpeptide,BNPELISAKit 大鼠腦素/腦尿肽(BNP)ELISA試劑盒 96T/48T 進(jìn)口分裝
CLIAKitforCTGF(Humanconnectivetissuegrowthfactor)ELISAKit人結(jié)締組織生長(zhǎng)因子規(guī)格：48T/96T
細(xì)胞糖原磷酸化酶(GLYCOGENPHOSPHORYLASE)活性酶連續(xù)循環(huán)比色法定量檢測(cè)試劑盒10次
Ratendotoxin,ETELISAKit大鼠內(nèi)毒素(ET)ELISA試劑盒規(guī)格：96T/48T
技術(shù)外包服務(wù):
★UBX結(jié)構(gòu)域域蛋白D2抗體規(guī)格 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測(cè)序、載體構(gòu)建等
★蛋白工程：原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。
|
|
|
|
|
